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am going to st thomas' hospital tomorrow..........: presentations 'food allergy'- a systemic disease - (Read 1,087 Times)
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Post Icon Posted: Jan 30th, 2008 at 01:08 pm

this should be interesting, but fear it might be a bit difficult for me to follow as this is for professionals!
I am not a doc!

the list of peadiatric allergists taking part is cool,
George du toit, Adam fox, Gidean Lack, Helen cox , Rachel de boer


however the last lecture 'new insights in to food allergy and asthma' is on last in the day, and I have to leave because of a meeting at my eldest teenagers school!

anyway will take notes and report, if anyone is interested.

sarah Smiley
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current allergies,

egg, peanut,beans, yeast extract, kiwi fruit, dog, cat, dustmite, mold, tree pollen, hay fever, and current unknown allergy.
this year so far, 6 reactions and used epi pen twice.

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Post Icon Posted: Jan 30th, 2008 at 01:11 pm

good luck!!!
you will do great! i saw your tv spot and i thought you were great!

Smiley
erin
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Post Icon Posted: Jan 30th, 2008 at 01:17 pm

In what Gideon Lack and his team have insights into??

OF COURSE we're 'interested!!!!' Smiley
Thanks-- and have fun!!


(PS.... someone's asked about outgrowing egg allergy down in the egg forum... was hoping you'd see it.)

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Post Icon Posted: Jan 30th, 2008 at 01:52 pm

Sounds wonderful Sarah. Enjoy and kidnap one of those allergists
Peg
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Post Icon Posted: Jan 30th, 2008 at 10:12 pm

Good Luck!! You will be Great!! Smiley
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http://www.foodallergyfaith.org
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Post Icon Posted: Jan 31st, 2008 at 08:27 am

how did it go?
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Post Icon Posted: Feb 4th, 2008 at 07:26 am

hello,
had a good time, was worried before hand that the talk would be so medical that I wouldnt understand it.
Was happy that most of it was something I already knew.

Please ingore spelling mistakes in bed with flu at the moment, ( more than likely caught on underground, my asthma is terrible as well, thank goodness you cant catch my germs reading this)

The last talk by Gideon Lack was interesting, talking about the LEAP study, heading 'can you prevent 'the allergic march'?
I am sure a link has been added here about this study in media. Lack is looking for a further 300 infants, and is happy/confidant that they will find them. ( I took some info to pass on )

other stuff, stats I have heard of,
4-8% children with asthma have food induced wheezing.

30/40% children with food allergy have asthma.

Aerosolied foods can induce allergic reactions, - asthma.
( jams jn pediatric '03 Pumphrey re.clin exp allergy) = fatal reactions also have ashtma in all cases.


New treatments interesting ( but dont hold out for magic wands yet!)
sublingual immunotherapy ( for hazel nut only )
In a RDBPC study
active group had intolerance to hazelnut
This justs increases tolerance , but only tempory halted threshold.
Stop treatment, and reactions to small amounts return.

Omalizumab
This prevents binding to IGE - Asthma a RDBPC study, ( 100 peanut allergic)
This omalizumab 'mops' up IGE
A very expensive 'magic bullet'
Tolerance increased from 0.5-9 peanuts
however not effective in 25% ( incd high dose group)
Not all patients respond to this treatement.
Thsi treatment can work well on Rhinitus and those that respond well, have asthma reduction as well, '30-40% of reduction of steriod drugs in children esp. Others stopped all steriods and inhalers. 40-60%
However costs big
per year, 3,100-15,400
medion cost 8,000 per

Good news for UK, NHS approved for severe persisitant allergic asthma. A life long treatment. This is required every two weeks. for teenagers and adults. All new good stuff.

Other interesting talks
Michael Perkin Peaediatric allergist, st Georges hos
'early influences on the development of allergic disease.

usual suspects ( us the parents)
family history of atpoic conditions ----breastfeeding (proctective of asthma)
longer breastfeeding, = slightly increased ezcema

only conclusion, do breastfed, avoid smoking. other breastfeeding rules can not be changed, due to lack of conclusive evidence. So although increased ezcema, experts agree breastfeeding if can be done , should be.

hygeine theory menitoned
we can avoid our children getting allergic disease, if when pregnant we
work with the large beasts of the field , perferably with a shovel, and a huge pile of the steaming brown stuff.

when we have infant , let them play with the cows etc.
( not pigs, they are not soooooo good!, pig farmers are not that well, often HAVE asthma etc)

Dogs, are good, but only if in home before birth, not so good after, none of this is true of cats.

or try unpasteurized milk , with the nasty risks that entails!!! ( not recommended)

Other factors that caught my eye,
calpol ( infant paracetamol)
early use of infant painkillers could be causing problem re -allergy disease.
Also high doeses of vit D has been shown to cause a problem .

repeated doses of antibiotics do show problem , and careful prescription use of antibotics recommended.

Probiotics
a high diversity of bowel flora during 1st week of life, may lead to being less atopic.
( on subject of probiotics added to infant formula)

data inconcluseive on reduction of atopic eczema long term. only slightly supportive under 6 months.



Big problem for those milk allergic or intolerant is the fact that pro-biotics are grown on WHEY protiens.


as for Omega 3
plenty of studies, all contadict.





I have more notes to add, didnt catch many details, wasnt happy that I couldnt get the study refs down before subject change , and my concentration was on the speaker!
I will add some more, but I need to top up my flu meds, find some tissues, and cough.

also, have to add that if you are in the states and going through the injections against hay fever , etc, if they are a year long or more, they have more than likey been watered down. The treatment that lasts longer = more money. ( this I heard outside the speakers hall, during coffee break) . I am hoping that this isnt true, as I dont like to think of medical people being money grubbing bastards.
Sorry about language, blame my high temp!!

will add more info when i can breathe.......................
sarah



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egg, peanut,beans, yeast extract, kiwi fruit, dog, cat, dustmite, mold, tree pollen, hay fever, and current unknown allergy.
this year so far, 6 reactions and used epi pen twice.
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Post Icon Posted: Feb 4th, 2008 at 07:48 am

thats really good info. i did hear about the asthma and the link between food allergies. our allergist told me not to be suprised if our son develops asthma. so far so good, knock on wood.


feel better soon
good job!
erin
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Post Icon Posted: Feb 4th, 2008 at 09:19 am

Thanks, Sarah! I love to read your version of it all. Interesting about the pig farmers; the one farmer I know who has asthma is a pig farmer. I don't know if he was that kind of farmer back when he developed it, though.
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U.S. - mom to PA daughter

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-- Cinderella, Into the Woods
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Post Icon Posted: Feb 4th, 2008 at 03:39 pm

Wow-- great stuff!! Hope you feel better soon. Smiley


As for the transient improvement on SLIT, that's very interesting. (disappointing, of course, but interesting nonetheless)

I wonder if that is what Boo's allergist was referring to? Hmmm....

The xolair stuff not working for 1 in 4 is so sad... and really perplexing, given how the stuff is supposed to work.




Vitamin D, huh? That would explain why all us northern latitude dwellers have epis, eh? Smiley (sigh-- does everyone recall last year's study about lack of Vit D as 'the culprit' in an epidemiological study?) Yes, its more contradictory information for the fire, I suppose.

Somehow it has to be my fault. It seems we can all be assured of that... LOL!!

Feel better soon! Smiley


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Post Icon Posted: Feb 5th, 2008 at 12:08 am

Great stuff, Sarah, thank-you.
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Post Icon Posted: Feb 6th, 2008 at 08:26 am

my other notes;
eczma /food allergy ( speaker Helen cox paed allergist)

risk of atopic disease, mother side 50% father 15% both 70%

( sorry couldnt read my notes very well!! to explain below!)

A genetric breakthough with regard to the genes that cause eczema have been discovered.

Children by 7yrs 40% still have ezcema that started when infants, but have high IGE, and other atopic diseases.


Interesting point of emoliants
large quantities should be used, inc bath oils/creams
Use at least 250gms-500gms per week.

ezcema before 1st three months indicates food allergy ( yeah, knew that, lived that one)

Eczema after 12 months can mean less chance of food allergy link.

SPT are not reliable to predict food allergy link/ ezcema, or a reliable test for wheat allergies.

Patch testing, again not good for predicting negative results.


Reaction pattern explained ( something that as an allergic parent have wittnessed a thousand times, and I noticed all the medical people taking this down )

delayed reaction, ( allergic) , day later= eczema .
most common delayed reactions causes by food, milk and wheat.

paitent history , with notes on cross reactions. eg soy may cross react to peanut.


dietary intervention.
remove food for 4 weeks
clear skin ( with treatments, steriods etc)
Food- re-introduce daily for 3 days. observe.

assesment of risk (home v hospital)
quanities of food to be given.


Infants formuas ;
Use formulas with completely changed proteins , =high % etc then work down after 6-8 weeks

hydrolized formula or amino acid formula.
If breastfed consider changeing to fromulas like neocate.

If breastfeeding remove milk and egg from maternal diet.

If formula required during 1st week of life, use only hydrolised milk formula ( like e.g neocate)
This is something that many european hosptials do as a matter of course, but uk does not.


formula such as goat milk, should never be used. Not suitable for infants under 1 yr. No safety data from the 'Nanny' company.
If allergic to cows milk lactose , goats milk has lactose as well, so not suitable alternative.

Have been withdrawn from NHS, and is no longer availble on prescription for some years, however CAN be brought from supermarkets. Something that should be taken from shelves in medical opinons.

Apparently, ezcema does slightly improve with donkey milk!!


Soilds,
delay or not?

During this presention, went over both uk advice and USA and the WHO guidelines. This is the UK result ,

No need to delay inroduction of allergic foods after 6 months.
INfact some studys show higher risk of developing allergies when food delayed. esp egg/ milk ( zutavern et all 04)

practical advicve
breastfeed 6 months
4-6 months
away from dairy/egg/nut/soy/fish/wheat free diet
6 months plus
add all highly allergic foods one at a time.

Soya
not first choice for milk allergic child. cross reactivity issues


Breastfeeding

WHO 03 suggest 6 months

prevent allergies?
protects for 3 months, positive effects on ezcema /asthma , but not allergic rhinitis

some studies are showing that breastfeeding may cause allergies ( sears et all 2002 Belgium 02)

maternal diet,
protective effect early months
no effect on asthma/allergic rhinitis 12-18 months

studies contradicts on this subject.

mothers health /nutrition at risk.


Can food allergy cause reflux/constipation?

reflux , yes, weak sphincter tentsion effected by food.
allergen links on to nerve endings on sphinter at top of stomach. gas pressure causes reflux.
usual suspects, milk/wheat

Constipation ( I enjoyed this talk, as have spent a great many years studying childrens poos!)

causes wheat/ milk or rare cases, soy ( very rare apparently)
normal hisotry of these children
6% food allergy link to anaphylaxis

constipation is common in children.
cows milk restriction can work well with some children
However and allergic child has
mucus
perniatal redness
intense pain
intense straining of normal stools.

good indicator of allergy = red face, red bum!!

children in great pain.

allergy again reacting to bowel wall, causing pain etc.

can start early, e.g breastfed
otehr atopic signs

when cause removed and small amount given, large symptoms shown.
( so little amounts have large reactions)

Treatment
change milk
if breastfeeding mother excludes from diet.
immuno modulation
laxatives ( limit symptoms esp in MFA)
but minimal use required.





so ends my notes on a really interesting day. BTW I dont have flu, but a chest infection. I am on some oral steriods as I cant take my inhaler, and some nice big antibiotics. Add all that to my daily IBS meds, and edmetriosis painkillers and I fairly rattle these days.
I quite like drugs.


sarah
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current allergies,

egg, peanut,beans, yeast extract, kiwi fruit, dog, cat, dustmite, mold, tree pollen, hay fever, and current unknown allergy.
this year so far, 6 reactions and used epi pen twice.
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Post Icon Posted: Feb 6th, 2008 at 08:50 am

WOW! Thanks Sarah, Smiley

Sure hope you get to feeling better (with a little less drugs Smiley )

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Have a blessed day!

DS(18) Allergic to peanuts, cashews & soy and is a terrific trombone player
DD(25) Allergic to Bactrim, & iodine. DD(28) NKA

Louisiana, USA
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Post Icon Posted: Feb 7th, 2008 at 05:26 pm

want to re-raise this.
also did want to transfer this info /link /post thingy to another allergy site ( talking allergies) just to save me the effort , as pretty poorly at the moment.

could any one help with that?
sarah
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current allergies,

egg, peanut,beans, yeast extract, kiwi fruit, dog, cat, dustmite, mold, tree pollen, hay fever, and current unknown allergy.
this year so far, 6 reactions and used epi pen twice.
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Post Icon Posted: Feb 7th, 2008 at 06:25 pm

This is the thread's link, Sarah.

http://allergy.hyperboards.com/index.php?action=view_topic&topic_id=2639

All you need to do is highlight it with mouse, then copy (control-C) and paste it in your post where you want it to appear.
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